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Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins

The Tetrahymena thermophila origin recognition complex (ORC) contains an integral RNA subunit, 26T RNA, which confers specificity to the amplified ribosomal DNA (rDNA) origin by base pairing with an essential cis-acting replication determinant—the type I element. Using a plasmid maintenance assay, w...

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Detalles Bibliográficos
Autores principales: Donti, Taraka R, Datta, Shibani, Sandoval, Pamela Y, Kapler, Geoffrey M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637336/
https://ncbi.nlm.nih.gov/pubmed/19153611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.282
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