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Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins

The Tetrahymena thermophila origin recognition complex (ORC) contains an integral RNA subunit, 26T RNA, which confers specificity to the amplified ribosomal DNA (rDNA) origin by base pairing with an essential cis-acting replication determinant—the type I element. Using a plasmid maintenance assay, w...

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Bibliografiske detaljer
Main Authors: Donti, Taraka R, Datta, Shibani, Sandoval, Pamela Y, Kapler, Geoffrey M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637336/
https://ncbi.nlm.nih.gov/pubmed/19153611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.282
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