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Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins
The Tetrahymena thermophila origin recognition complex (ORC) contains an integral RNA subunit, 26T RNA, which confers specificity to the amplified ribosomal DNA (rDNA) origin by base pairing with an essential cis-acting replication determinant—the type I element. Using a plasmid maintenance assay, w...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637336/ https://ncbi.nlm.nih.gov/pubmed/19153611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.282 |
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