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Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins

The Tetrahymena thermophila origin recognition complex (ORC) contains an integral RNA subunit, 26T RNA, which confers specificity to the amplified ribosomal DNA (rDNA) origin by base pairing with an essential cis-acting replication determinant—the type I element. Using a plasmid maintenance assay, w...

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Detalhes bibliográficos
Main Authors: Donti, Taraka R, Datta, Shibani, Sandoval, Pamela Y, Kapler, Geoffrey M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637336/
https://ncbi.nlm.nih.gov/pubmed/19153611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.282
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