Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins

The Tetrahymena thermophila origin recognition complex (ORC) contains an integral RNA subunit, 26T RNA, which confers specificity to the amplified ribosomal DNA (rDNA) origin by base pairing with an essential cis-acting replication determinant—the type I element. Using a plasmid maintenance assay, w...

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Main Authors: Donti, Taraka R, Datta, Shibani, Sandoval, Pamela Y, Kapler, Geoffrey M
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637336/
https://ncbi.nlm.nih.gov/pubmed/19153611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.282
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