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Analysis of a conserved RGE/RGD motif in HCV E2 in mediating entry

BACKGROUND: Hepatitis C virus (HCV) encodes two transmembrane glycoproteins E1 and E2 which form a heterodimer. E1 is believed to mediate fusion while E2 has been shown to bind cellular receptors. It is clear that HCV uses a multi-receptor complex to gain entry into susceptible cells, however key el...

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Bibliografiske detaljer
Main Authors: Rothwangl, Katharina B, Rong, Lijun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637243/
https://ncbi.nlm.nih.gov/pubmed/19171049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-12
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