Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivation in cultured cortical neurons

We tested whether rosuvastatin (RST) protected against oxygen-glucose deprivation (OGD)-induced cell death in primary rat cortical neuronal cultures. OGD reduced neuronal viability (%naive controls, mean ± SE, n = 24–96, P < 0.05) to 44 ± 1%, but 3-day pretreatment with RST (5 μM) increased survi...

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Detalhes bibliográficos
Main Authors: Domoki, Ferenc, Kis, Béla, Gáspár, Tamás, Snipes, James A., Parks, John S., Bari, Ferenc, Busija, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Nervous System Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636993/
https://ncbi.nlm.nih.gov/pubmed/18971391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00366.2008
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