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Prolonged treatment of porcine pulmonary artery with nitric oxide decreases cGMP sensitivity and cGMP-dependent protein kinase specific activity

A cultured porcine pulmonary artery (PA) model was used to examine the effects of prolonged nitric oxide (NO) treatment on the response to acutely applied NO, cGMP analog, or atrial natriuretic peptide (ANP). Twenty-four-hour treatment with the NO donor (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Perkins, William J., Warner, David O., Jones, Keith A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636956/
https://ncbi.nlm.nih.gov/pubmed/18952758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90318.2008
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