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Prolonged treatment of porcine pulmonary artery with nitric oxide decreases cGMP sensitivity and cGMP-dependent protein kinase specific activity

A cultured porcine pulmonary artery (PA) model was used to examine the effects of prolonged nitric oxide (NO) treatment on the response to acutely applied NO, cGMP analog, or atrial natriuretic peptide (ANP). Twenty-four-hour treatment with the NO donor (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amin...

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Detaylı Bibliyografya
Asıl Yazarlar: Perkins, William J., Warner, David O., Jones, Keith A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636956/
https://ncbi.nlm.nih.gov/pubmed/18952758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90318.2008
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