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Novel human bronchial epithelial cell lines for cystic fibrosis research

Immortalization of human bronchial epithelial (hBE) cells often entails loss of differentiation. Bmi-1 is a protooncogene that maintains stem cells, and its expression creates cell lines that recapitulate normal cell structure and function. We introduced Bmi-1 and the catalytic subunit of telomerase...

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Autores principales: Fulcher, M. L., Gabriel, S. E., Olsen, J. C., Tatreau, J. R., Gentzsch, M., Livanos, E., Saavedra, M. T., Salmon, P., Randell, S. H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636952/
https://ncbi.nlm.nih.gov/pubmed/18978040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90314.2008
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