Noninvasive prediction of tumor responses to gemcitabine using positron emission tomography

Gemcitabine (2′,2′-difluorodeoxycytidine, dFdC) and cytosine arabinoside (cytarabine, ara-C) represent a class of nucleoside analogs used in cancer chemotherapy. Administered as prodrugs, dFdC and ara-C are transported across cell membranes and are converted to cytotoxic derivatives through consecut...

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Bibliographic Details
Main Authors: Laing, Rachel E., Walter, Martin A., Campbell, Dean O., Herschman, Harvey R., Satyamurthy, Nagichettiar, Phelps, Michael E., Czernin, Johannes, Witte, Owen N., Radu, Caius G.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636738/
https://ncbi.nlm.nih.gov/pubmed/19196993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812890106
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