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Attenuation of Obliterative Bronchiolitis by a CXCR4 antagonist in the murine heterotopic tracheal transplant model

Long-term success in lung transplantation is limited by obliterative bronchiolits (OB), while the mechanism for this disease is not well-understood. Chemokine SDF-1 and its receptor CXCR4 have been reported to be involved in several fibrogenic processes by recruiting inflammatory and fibroblast prog...

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Bibliographic Details
Main Authors: Xu, Jianguo, Torres, Edilson, Mora, Ana, Shim, Hyunsuk, Ramirez, Allan, Neujahr, David, Brigham, Kenneth L., Rojas, Mauricio
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636706/
https://ncbi.nlm.nih.gov/pubmed/19059110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2008.08.010
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