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Role of the SDF-1/CXCR4 Axis in the Pathogenesis of Lung Injury and Fibrosis

Stromal cell–derived factor-1 (SDF-1) participates in mobilizing bone marrow–derived stem cells, via its receptor CXCR4. We studied the role of the SDF-1/CXCR4 axis in a rodent model of bleomycin-induced lung injury in C57BL/6 wild-type and matrix metalloproteinase (MMP)-9 knockout mice. After intra...

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Detalhes bibliográficos
Main Authors: Xu, Jianguo, Mora, Ana, Shim, Hyunsuk, Stecenko, Arlene, Brigham, Kenneth L., Rojas, Mauricio
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994230/
https://ncbi.nlm.nih.gov/pubmed/17463394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0187OC
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