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Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer

Notch3 gene amplification has recently been identified in ovarian cancer but the Notch3 effectors that are involved in the development of ovarian cancer remain elusive. In this study, we have identified Pbx1, a proto-oncogene in hematopoietic malignancy, as a Notch3 target gene. Pbx1 expression is t...

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Main Authors: Park, Joon T, Shih, Ie-Ming, Wang, Tian-Li
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636690/
https://ncbi.nlm.nih.gov/pubmed/18974129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0517
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