A Cooperative Interaction between Nontranslated RNA Sequences and NS5A Protein Promotes In Vivo Fitness of a Chimeric Hepatitis C/GB Virus B

GB virus B (GBV-B) is closely related to hepatitis C virus (HCV), infects small non-human primates, and is thus a valuable surrogate for studying HCV. Despite significant differences, the 5′ nontranslated RNAs (NTRs) of these viruses fold into four similar structured domains (I-IV), with domains II-...

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Detalhes bibliográficos
Principais autores: Warter, Lucile, Cohen, Lisette, Benureau, Yann, Chavez, Deborah, Yang, Yan, Bodola, Francis, Lemon, Stanley M., Traboni, Cinzia, Lanford, Robert E., Martin, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635954/
https://ncbi.nlm.nih.gov/pubmed/19204793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004419
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