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Inclusion-Body Myositis: Muscle-Fiber Molecular Pathology and Possible Pathogenic Significance of Its Similarity to Alzheimer and Parkinson Disease Brains

Sporadic inclusion-body myositis (s-IBM), the most common muscle disease of older persons, is of unknown cause and lacks successful treatment. Here we summarize diagnostic criteria and discuss our current understanding of the steps in the pathogenic cascade. While it is agreed that both degeneration...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Askanas, Valerie, Engel, W. King
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635944/
https://ncbi.nlm.nih.gov/pubmed/18974994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-008-0449-0
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