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Identification of small-molecule inducers of pancreatic β-cell expansion

To identify small molecules that can induce β-cell replication, a large chemical library was screened for proliferation of growth-arrested, reversibly immortalized mouse β cells by using an automated high-throughput screening platform. A number of structurally diverse, active compounds were identifi...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Weidong, Walker, John R., Wang, Xia, Tremblay, Matthew S., Lee, Jae Wook, Wu, Xu, Schultz, Peter G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635822/
https://ncbi.nlm.nih.gov/pubmed/19164755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811848106
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