Laddar...
Rab5 modulates mutant huntingtin aggregation/toxicity in cell and fly models via macroautophagy
Huntington's disease (HD) is caused by a polyglutamine expansion mutation in huntingtin that makes the protein toxic and aggregate-prone. The subcellular localisation of huntingtin and many of its interactors suggest a role in endocytosis, and recently it has been shown that huntingtin interact...
Sparad:
| Huvudupphovsmän: | , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2008
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635563/ https://ncbi.nlm.nih.gov/pubmed/18430781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.025726 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|