Biological activities of synthetic lipid A analogs: pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate.

Chemically synthesized lipid A analogs were investigated for several endotoxic activities, including pyrogenicity, lethal toxicity, anticomplement activity, and the capacity to gelate Limulus amoebocyte lysate in comparison to natural lipid A. The synthetic preparations contained D-glucosamine or D-...

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Hauptverfasser: Tanamoto, K, Zähringer, U, McKenzie, G R, Galanos, C, Rietschel, E T, Lüderitz, O, Kusumoto, S, Shiba, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1984
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC263535/
https://ncbi.nlm.nih.gov/pubmed/6715042
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