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Constitutive Internalization of G Protein-coupled Receptors and G Proteins via Clathrin-independent Endocytosis

Although agonist-dependent endocytosis of G protein-coupled receptors (GPCRs) as a means to modulate receptor signaling has been widely studied, the constitutive endocytosis of GPCRs has received little attention. Here we show that two prototypical class I GPCRs, the β2 adrenergic and M3 muscarinic...

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Detalhes bibliográficos
Main Authors: Scarselli, Marco, Donaldson, Julie G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635037/
https://ncbi.nlm.nih.gov/pubmed/19033440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806819200
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