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A TAG on to the neurogenic functions of APP
The proteolytic processing of amyloid β precursor protein (APP) has long been studied because of its association with the pathology of Alzheimer's disease (AD). The ectodomain of APP is shed by α- or β-secretase cleavage. The remaining membrane bound stub can then undergo regulated intramembran...
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Glavni autori: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Landes Bioscience
2008
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634997/ https://ncbi.nlm.nih.gov/pubmed/19262125 |
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