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A TAG on to the neurogenic functions of APP

The proteolytic processing of amyloid β precursor protein (APP) has long been studied because of its association with the pathology of Alzheimer's disease (AD). The ectodomain of APP is shed by α- or β-secretase cleavage. The remaining membrane bound stub can then undergo regulated intramembran...

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Bibliografski detalji
Glavni autori: Ma, Quan-Hong, Bagnard, Dominique, Xiao, Zhi-Cheng, Dawe, Gavin S
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634997/
https://ncbi.nlm.nih.gov/pubmed/19262125
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