High CD8+ T Cell Activation Marks a Less Differentiated HIV-1 Specific CD8+ T Cell Response that Is Not Altered by Suppression of Viral Replication

BACKGROUND: The relationship of elevated T cell activation to altered T cell differentiation profiles, each defining features of HIV-1 infection, has not been extensively explored. We hypothesized that anti-retroviral suppression of T cell activation levels would lead to alterations in the T cell di...

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Detalhes bibliográficos
Main Authors: Barbour, Jason D., Ndhlovu, Lishomwa C., Xuan Tan, Qi, Ho, Terence, Epling, Lorrie, Bredt, Barry M., Levy, Jay A., Hecht, Frederick M., Sinclair, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634967/
https://ncbi.nlm.nih.gov/pubmed/19198651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004408
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