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Recombinant Adenoviruses Expressing Steatosis-Associated Hepatitis C Virus Genotype 3 Core Protein Produce Intracellular Lipid Accumulation in Cultured and Primary Hepatocytes
Steatosis, or “fatty liver”, is a common finding in Hepatitis C virus (HCV) infection and reflects dysregulation of lipid homeostasis. HCV Core protein causes lipid accumulation when expressed in cultured cell lines, which data now indicates is a critical step for HCV replication, assembly and relea...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634964/ https://ncbi.nlm.nih.gov/pubmed/19010361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2008.10.008 |
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