Uroporphyrin accumulation produced by halogenated biphenyls in chick-embryo hepatocytes. Reversal of the accumulation by piperonyl butoxide.

Cultures of chick-embryo hepatocytes were used to study the mechanism by which 3,4,3',4'-tetrachlorobiphenyl and 2,4,5,3',4'-pentabromobiphenyl cause accumulation of uroporphyrin. In a previous paper, an isoenzyme of cytochrome P-450 induced by 3-methylcholanthrene had been impli...

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Detalhes bibliográficos
Main Authors: Sinclair, P R, Bement, W J, Bonkovsky, H L, Lambrecht, R W, Frezza, J E, Sinclair, J F, Urquhart, A J, Elder, G H
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1146948/
https://ncbi.nlm.nih.gov/pubmed/3026315
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