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Bidirectional Ca(2+)-dependent control of mitochondrial dynamics by the Miro GTPase

Calcium oscillations suppress mitochondrial movements along the microtubules to support on-demand distribution of mitochondria. To activate this mechanism, Ca(2+) targets a yet unidentified cytoplasmic factor that does not seem to be a microtubular motor or a kinase/phosphatase. Here, we have studie...

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Detalhes bibliográficos
Main Authors: Saotome, Masao, Safiulina, Dzhamilja, Szabadkai, György, Das, Sudipto, Fransson, Åsa, Aspenstrom, Pontus, Rizzuto, Rosario, Hajnóczky, György
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634948/
https://ncbi.nlm.nih.gov/pubmed/19098100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808953105
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