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Protein kinase A inhibits a consolidated form of memory in Drosophila

Increasing activity of the cAMP/protein kinase A (PKA) pathway has often been proposed as an approach to improve memory in various organisms. However, here we demonstrate that single-point mutations, which decrease PKA activity, dramatically improve aversive olfactory memory in Drosophila. These mut...

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Detalhes bibliográficos
Main Authors: Horiuchi, Junjiro, Yamazaki, Daisuke, Naganos, Shintaro, Aigaki, Toshiro, Saitoe, Minoru
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634933/
https://ncbi.nlm.nih.gov/pubmed/19075226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810119105
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