Acute Inhibition of PKA Activity at Old Ages Ameliorates Age-Related Memory Impairment in Drosophila

Age-related memory impairment (AMI) is a critical and debilitating phenotype of brain aging, but its underlying molecular mechanisms are largely unknown. In Drosophila, AMI is highly correlated with PKA activity in the mushroom bodies, neural centers essential for forming associative olfactory memor...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Yamazaki, Daisuke, Horiuchi, Junjiro, Miyashita, Tomoyuki, Saitoe, Minoru
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2010
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Brief Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633660/
https://ncbi.nlm.nih.gov/pubmed/21084612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3229-10.2010
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