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UA62784; a novel inhibitor of CENP-E kinesin-like protein

Pancreatic carcinoma is the fourth-leading cause of death from cancer. Novel targets and therapeutic options are needed to aid in the treatment of pancreatic cancer. The compound UA62784 is a novel fluorenone with inhibitory activity against the CENP-E kinesin-like protein. UA62784 was isolated due...

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Detalhes bibliográficos
Main Authors: Henderson, Meredith C., Shaw, Yeng-Jeng Y., Wang, Hong, Han, Haiyong, Hurley, Laurence H., Flynn, Gary, Dorr, Robert T., Von Hoff, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634858/
https://ncbi.nlm.nih.gov/pubmed/19139111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0789
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