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ER chaperones participate in HCMV US2-mediated degradation of class I MHC molecules
Human cytomegalovirus (HCMV) is a β-herpes virus that prevents the surface expression of class I MHC molecules in an attempt to escape recognition via cytotoxic CD8+ T cells. The HCMV US2 and US11 gene products induce class I down regulation during the early phase of HCMV infection by facilitating t...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634742/ https://ncbi.nlm.nih.gov/pubmed/18420789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.83516-0 |
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