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Promoter CpG methylation in cancer cells contributes to the regulation of MUC4
Mucin 4 (MUC4) is a high molecular weight transmembrane mucin that is overexpressed in many carcinomas and is a risk factor associated with a poor prognosis. In this study, we show that the DNA methylation pattern is intimately correlated with MUC4 expression in breast, lung, pancreas and colon canc...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634723/ https://ncbi.nlm.nih.gov/pubmed/19127263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604845 |
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