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Oncogenic mutations in GNAQ occur early in uveal melanoma

PURPOSE: Early/initiating oncogenic mutations have been identified for many cancers, but such mutations remain unidentified in uveal melanoma (UM). An extensive search for such mutations was undertaken, focusing on the RAF/MEK/ERK pathway, which is often the target of initiating mutations in other t...

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Detalhes bibliográficos
Main Authors: Onken, Michael D., Worley, Lori A., Long, Meghan D., Duan, Shenghui, Council, M. Laurin, Bowcock, Anne M., Harbour, J. William
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634606/
https://ncbi.nlm.nih.gov/pubmed/18719078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2145
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