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Microarray and pathway analysis reveals decreased CDC25A and increased CDC42 associated with slow growth of BCL2 overexpressing immortalized breast cell line

Bcl-2 is an anti-apoptotic protein that is frequently overex-pressed in cancer cells but its role in carcinogenesis is not clear. We are interested in how Bcl-2 expression affects non-cancerous breast cells and its role in the cell cycle. We prepared an MCF10A breast epithelial cell line that stably...

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Detalhes bibliográficos
Principais autores: Long, Jacquelyn M., Bell, Charles W., Fagg, W. Samuel, Kushman, Mary E., Becker, Kevin G., McCubrey, James A., Farwell, Mary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634598/
https://ncbi.nlm.nih.gov/pubmed/18838868
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