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Crosstalk between CXCR4/SDF-1 and VLA-4/VCAM-1 pathways regulates neutrophil retention in the bone marrow

Neutrophil retention in and release from the bone marrow is a critical process that remains incompletely understood. Previous work has implicated the CXCR4/SDF-1 chemokine axis in the marrow retention of neutrophils, yet the adhesion pathways responsible for this retention are unknown. Since α4β1 in...

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Bibliographische Detailangaben
Hauptverfasser: Petty, Joseph M., Lenox, Christopher C., Weiss, Daniel J., Poynter, Matthew E., Suratt, Benjamin T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633729/
https://ncbi.nlm.nih.gov/pubmed/19109194
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