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Aggregation of Expanded Huntingtin in the Brains of Patients With Huntington Disease

Huntingtin containing an expanded polyglutamine causes neuronal death and Huntington disease. Although expanded huntingtin is found in virtually every cell type, its toxicity is limited to neurons of certain areas of the brain, such as cortex and caudate/putamen. In affected areas of the brain, expa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hoffner, Guylaine, Souès, Sylvie, Djian, Philippe
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633704/
https://ncbi.nlm.nih.gov/pubmed/19172113
Tagiau: Ychwanegu Tag
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