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Aggregation of Expanded Huntingtin in the Brains of Patients With Huntington Disease

Huntingtin containing an expanded polyglutamine causes neuronal death and Huntington disease. Although expanded huntingtin is found in virtually every cell type, its toxicity is limited to neurons of certain areas of the brain, such as cortex and caudate/putamen. In affected areas of the brain, expa...

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Autores principales: Hoffner, Guylaine, Souès, Sylvie, Djian, Philippe
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633704/
https://ncbi.nlm.nih.gov/pubmed/19172113
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