Transcriptional Profiling in Pathogenic and Non-Pathogenic SIV Infections Reveals Significant Distinctions in Kinetics and Tissue Compartmentalization

Simian immunodeficiency virus (SIV) infection leads to AIDS in experimentally infected macaques, whereas natural reservoir hosts exhibit limited disease and pathology. It is, however, unclear how natural hosts can sustain high viral loads, comparable to those observed in the pathogenic model, withou...

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Bibliographic Details
Main Authors: Lederer, Sharon, Favre, David, Walters, Kathie-Anne, Proll, Sean, Kanwar, Bittoo, Kasakow, Zeljka, Baskin, Carole R., Palermo, Robert, McCune, Joseph M., Katze, Michael G.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633618/
https://ncbi.nlm.nih.gov/pubmed/19214219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000296
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