Transcriptional Profiling in Pathogenic and Non-Pathogenic SIV Infections Reveals Significant Distinctions in Kinetics and Tissue Compartmentalization

Simian immunodeficiency virus (SIV) infection leads to AIDS in experimentally infected macaques, whereas natural reservoir hosts exhibit limited disease and pathology. It is, however, unclear how natural hosts can sustain high viral loads, comparable to those observed in the pathogenic model, withou...

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Detalhes bibliográficos
Main Authors: Lederer, Sharon, Favre, David, Walters, Kathie-Anne, Proll, Sean, Kanwar, Bittoo, Kasakow, Zeljka, Baskin, Carole R., Palermo, Robert, McCune, Joseph M., Katze, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633618/
https://ncbi.nlm.nih.gov/pubmed/19214219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000296
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