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A genetically encoded fluorescent reporter of ATP/ADP ratio

A fluorescent sensor of adenylate nucleotides was constructed by combining a circularly permuted variant of green fluorescent protein with a bacterial regulatory protein, GlnK1, from Methanococcus jannaschii. The affinity for Mg-ATP is below 100 nM, as seen for the other members of the bacterial PII...

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Bibliographic Details
Main Authors: Berg, Jim, Hung, Yin Pun, Yellen, Gary
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633436/
https://ncbi.nlm.nih.gov/pubmed/19122669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1288
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