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Human BRE1 Is an E3 Ubiquitin Ligase for Ebp1 Tumor Suppressor
Human Bre1, an E3 ligase for H2B monoubiquitination, binds p53 and enhances activator-dependent transcription. Ebp1, an ErbB3 receptor-binding protein, inhibits cell proliferation and acts as a tumor suppressor. Here, we show that hBre1 acts as an E3 ubiquitin ligase for Ebp1 tumor suppressor and pr...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633391/ https://ncbi.nlm.nih.gov/pubmed/19037095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-09-0983 |
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