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E3 ubiquitin ligase Bre1 couples sister chromatid cohesion establishment to DNA replication in Saccharomyces cerevisiae

Bre1, a conserved E3 ubiquitin ligase in Saccharomyces cerevisiae, together with its interacting partner Lge1, are responsible for histone H2B monoubiquitination, which regulates transcription, DNA replication, and DNA damage response and repair, ensuring the structural integrity of the genome. Dele...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zhang, Wei, Yeung, Clarence Hue Lok, Wu, Liwen, Yuen, Karen Wing Yee
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699866/
https://ncbi.nlm.nih.gov/pubmed/29058668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28231
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