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Supervillin Reorganizes the Actin Cytoskeleton and Increases Invadopodial Efficiency

Tumor cells use actin-rich protrusions called invadopodia to degrade extracellular matrix (ECM) and invade tissues; related structures, termed podosomes, are sites of dynamic ECM interaction. We show here that supervillin (SV), a peripheral membrane protein that binds F-actin and myosin II, reorgani...

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Bibliografiske detaljer
Main Authors: Crowley, Jessica L., Smith, Tara C., Fang, Zhiyou, Takizawa, Norio, Luna, Elizabeth J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633381/
https://ncbi.nlm.nih.gov/pubmed/19109420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0867
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