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Supervillin Reorganizes the Actin Cytoskeleton and Increases Invadopodial Efficiency
Tumor cells use actin-rich protrusions called invadopodia to degrade extracellular matrix (ECM) and invade tissues; related structures, termed podosomes, are sites of dynamic ECM interaction. We show here that supervillin (SV), a peripheral membrane protein that binds F-actin and myosin II, reorgani...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633381/ https://ncbi.nlm.nih.gov/pubmed/19109420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0867 |
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