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A Myopathy-linked Desmin Mutation Perturbs Striated Muscle Actin Filament Architecture
Desmin interacts with nebulin establishing a direct link between the intermediate filament network and sarcomeres at the Z-discs. Here, we examined a desmin mutation, E245D, that is located within the coil IB (nebulin-binding) region of desmin and that has been reported to cause human cardiomyopathy...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633376/ https://ncbi.nlm.nih.gov/pubmed/19005210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-07-0753 |
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