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Prominin1 marks intestinal stem cells that are susceptible to neoplastic transformation
Cancer stem cells (CSC) are remarkably similar to normal stem cells: both self-renew, are multipotent and express common surface markers, e.g., PROMININ-1 (PROM1, CD133)1. What remains unclear is whether CSC are the direct progeny of mutated stem cells, or more mature cells that reacquire stem cell...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633030/ https://ncbi.nlm.nih.gov/pubmed/19092805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07589 |
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