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Ionizing radiation activates expression of FOXO3a, Fas ligand, Bim, and induces cell apoptosis

Genotoxic stress such as ionizing radiation can induce DNA damage and promote cell-cycle arrest or apoptosis through either a p53-dependent or - independent pathway. Recently, members of the FOXO Forkhead transcription factor family have been implicated in playing a role in both DNA repair and apopt...

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Detalhes bibliográficos
Main Authors: Yang, Jer-Yen, Xia, Weiya, Hu, Mickey C-T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632978/
https://ncbi.nlm.nih.gov/pubmed/16865280
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