Radiation and stress-induced apoptosis: A role for Fas/Fas ligand interactions

The lpr gene encodes a defective form of Fas, a cell surface protein that mediates apoptosis. This defect blocks apoptotic deletion of autoreactive T and B cells, leading to lymphoproliferation and lupus-like autoantibody production. The effects of the lpr Fas mutation on other kinds of physiologica...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Reap, Elizabeth A., Roof, Kevin, Maynor, Kenrick, Borrero, Michelle, Booker, Jessica, Cohen, Philip L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9159145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.11.5750
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