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Nortriptyline Protects Mitochondria and Reduces Cerebral Ischemia/Hypoxia Injury
BACKGROUND AND PURPOSE: Nortriptyline, an antidepressant, was identified as a strong inhibitor of mitochondrial permeability transition by our screening of a library of 1040 drugs. Because mitochondrial permeability transition and consequent mitochondrial dysfunction have been implicated in acute ne...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2632945/ https://ncbi.nlm.nih.gov/pubmed/18174477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.107.496810 |
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