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The novel p53 target gene IRF2BP2 participates in cell survival during the p53 stress response

The tumor suppressor p53 contributes to the cellular fate after genotoxic insults, mainly through the regulation of target genes, thereby allowing e.g. repair mechanisms resulting in cell survival or inducing apoptosis. Unresolved so far is the issue, which exact mechanisms lead to one or the other...

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Bibliografiske detaljer
Main Authors: Koeppel, Max, van Heeringen, Simon J., Smeenk, Leonie, Navis, Anna C., Janssen-Megens, Eva M., Lohrum, Marion
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632907/
https://ncbi.nlm.nih.gov/pubmed/19042971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn940
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