The novel p53 target gene IRF2BP2 participates in cell survival during the p53 stress response

The tumor suppressor p53 contributes to the cellular fate after genotoxic insults, mainly through the regulation of target genes, thereby allowing e.g. repair mechanisms resulting in cell survival or inducing apoptosis. Unresolved so far is the issue, which exact mechanisms lead to one or the other...

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Main Authors: Koeppel, Max, van Heeringen, Simon J., Smeenk, Leonie, Navis, Anna C., Janssen-Megens, Eva M., Lohrum, Marion
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632907/
https://ncbi.nlm.nih.gov/pubmed/19042971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn940
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