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Conformational Changes and Slow Dynamics through Microsecond Polarized Atomistic Molecular Simulation of an Integral Kv1.2 Ion Channel

Structure and dynamics of voltage-gated ion channels, in particular the motion of the S4 helix, is a highly interesting and hotly debated topic in current membrane protein research. It has critical implications for insertion and stabilization of membrane proteins as well as for finding how transitio...

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Main Authors: Bjelkmar, Pär, Niemelä, Perttu S., Vattulainen, Ilpo, Lindahl, Erik
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632863/
https://ncbi.nlm.nih.gov/pubmed/19229308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000289
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