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FDH-induced JNK pathways diverge at the JNK substrate level in cells with different p53 status
FDH (10-formyltetrahydrofolate dehydrogenase) suppresses cancer cell proliferation through p53 dependent apoptosis but also induces strong cytotoxicity in p53-deficient prostate cells. In the present study we have demonstrated that FDH induces apoptosis in PC-3 prostate cells through simultaneous ac...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2632845/ https://ncbi.nlm.nih.gov/pubmed/19147541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0309 |
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