Role of the domain encompassing Arg(304)–Ile(328) in rat P2X(2) receptor conformation revealed by alterations in complex glycosylation at Asn(298)

The final 25 amino acids of the ectodomain of the P2X receptors, immediately prior to the second TM (transmembrane domain) (pre-TM2: Arg(304)–Ile(328) in rat P2X(2)), are highly conserved. Whole-cell patch clamp recordings showed that single cysteine substitutions in the N-terminal half of pre-TM2 (...

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Detalhes bibliográficos
Main Authors: Young, Mark T., Zhang, Yi-Hong, Cao, Lishuang, Broomhead, Helen, Jiang, Lin-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632800/
https://ncbi.nlm.nih.gov/pubmed/18616429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081182
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