Conformational Changes of Congenital FVII Variants with Defective Binding to Tissue Factor ARG304GLN (FVII Padua), ARG 304TRP (FVII Nagoya) and ARG79GLN (FVII Shinjo or Tondabayashi)

BACKGROUND: The relation between Factor VII (FVII) and tissue thromboplastin is not completely clarified, yet. Three FVII abnormalities, FVII Padua (Arg304Gln), FVII Nagoya (Arg304Trp) and FVII Shinjo or Tondabayshi (Arg79Gln) show different FVII activity according to the tissue Tissue Factor (TF) u...

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Detalhes bibliográficos
Main Authors: Cristiani, Andrea, Vettore, Silvia, Sambado, Luisa, Bulfone, Alessandro, Moro, Stefano, Girolami, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Master Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884787/
https://ncbi.nlm.nih.gov/pubmed/24711753
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