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Biomimetic total synthesis of tricycloillicinone and mechanistic studies toward the rearrangement of prenyl phenyl ethers

The paper describes a short and biomimetic synthesis of tricycloillicinone, which was found to enhance the action of choline acetyltransferase (ChAT). The synthetic route has two critical reactions: bulky, oxygenophilic methylaluminum bis(4-bromo-2,6-di-tert-butylphenoxide) (MABR) promoted rearrange...

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Autori principali: Lei, Xiaoguang, Dai, Mingji, Hua, Zihao, Danishefsky, Samuel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632774/
https://ncbi.nlm.nih.gov/pubmed/19890380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.07.184
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