Disruption of Vps4 and JNK Function in Drosophila Causes Tumour Growth

Several regulators of endocytic trafficking have recently been identified as tumour suppressors in Drosophila. These include components of the endosomal sorting complex required for transport (ESCRT) machinery. Disruption of subunits of ESCRT-I and –II leads to cell-autonomous endosomal accumulation...

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Hlavní autoři: Rodahl, Lina M., Haglund, Kaisa, Sem-Jacobsen, Catherine, Wendler, Franz, Vincent, Jean-Paul, Lindmo, Karine, Rusten, Tor Erik, Stenmark, Harald
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632753/
https://ncbi.nlm.nih.gov/pubmed/19194501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004354
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