Disruption of Vps4 and JNK Function in Drosophila Causes Tumour Growth

Several regulators of endocytic trafficking have recently been identified as tumour suppressors in Drosophila. These include components of the endosomal sorting complex required for transport (ESCRT) machinery. Disruption of subunits of ESCRT-I and –II leads to cell-autonomous endosomal accumulation...

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Detalhes bibliográficos
Main Authors: Rodahl, Lina M., Haglund, Kaisa, Sem-Jacobsen, Catherine, Wendler, Franz, Vincent, Jean-Paul, Lindmo, Karine, Rusten, Tor Erik, Stenmark, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632753/
https://ncbi.nlm.nih.gov/pubmed/19194501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004354
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