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Implications of Clinical Trial Design on Sample Size Requirements
The primary goal in designing a randomized controlled clinical trial (RCT) is to minimize bias in the estimate of treatment effect. Randomized group assignment, double-blinded assessments, and control or comparison groups reduce the risk of bias. The design must also provide sufficient statistical p...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2008
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2632464/ https://ncbi.nlm.nih.gov/pubmed/18469326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbn035 |
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